Influence of opioid on the relationship between effect-site concentration of propofol at loss of response and that at maintenance of anesthesia

Influence of opiod on effect of propofol - Influence of opiod on effect of propofol

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042785

Enrollment

Registered

2020-12-20

Start date

2020-12-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast tumor and gall stone

Interventions

No remifentanil is used. Ce of remifentanil was controlled at 1.0 ng/mL. Ce of remifentanil was controlled at 2.0 ng/mL.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patinets who satisfied the following all conditions. 1) Age is 20 or more. 2) Hospitalized patient 3) both gender 4) ASA-PS is I or II 5) Low surgical stress 6) patients who scheduled lapaloscopic cholecystectcomy or mannmectomy 7) patients who agreed after informed consent

Exclusion criteria

Exclusion criteria: patients who matched either of following conditions. 1) patients who had severe liver dysfunction or severe renal dysfunction 2) pregnant or lactating women 3) patients who are medicated a drug that had interaction with propofol 4) patients who had neurological disorder 5) patients who showed allergy to propofol 6) ASA-PS III or more 7) obesity (BMI is 35 or more)

Design outcomes

Primary

Measure	Time frame
We investigate the relationship between Ce-LOR, Ce-alpha and Ce-OBS when effect-site concentration of remifentanil was kept 0, 0.1 or 0.2 ng/mL.	—

Countries

Japan

Contacts

Public ContactSatoshi Hagihira

Kansai Medical University Department of Anesthesiology

hagihirs@hirakata.kmu.a.cjp072-804-2683

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026