Impact of anesthetic induction with Etomidate, Thiopentone and Propofol on regional cerebral oxygenation: An observational study in patients with traumatic brain injury

Impact of anesthetic induction with Etomidate, Thiopentone and Propofol on regional cerebral oxygenation: An observational study in patients with traumatic brain injury - IETP-RCO2

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000042780

Enrollment

115

Registered

2022-06-30

Start date

2020-02-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Completed in December 2021

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient of either gender aged 18 years and above undergoing emergency cranial surgery for acute TBI with moderate or severe GCS (12-3)

Exclusion criteria

Exclusion criteria: (i) No consent (ii) Pregnant patients (iii) Contraindication to study drugs (haemodynamically unstable patient, ASA 3,4 or 5) (iv) Patients with maxillofacial injuries (v) Patients with factors that will affect NIRS values (like underlying scalp haematoma or pneumocephalus) (vi) Airway contamination or likelihood of pulmonary aspiration (vii) Patients already intubated in casualty ward

Design outcomes

Primary

Measure	Time frame
Improvement in prognosis of patient by stable anesthetic induction.	—

Countries

Asia(except Japan)

Contacts

Public ContactKUNAL KUMAR

NATIONAL INSTITUTE OF MENTAL HEALTH AND NEURO SCIENCES NEUROANESTHESIA AND NEURO CRITICAL CARE

kunaal_kumar@yahoo.com7018388348

Outcome results