Healthy adult
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Healthy male and female between 20 and 70 years old 2) Individuals who has subjective symptoms of cold intolerance 3) Individuals who can refrain from over drinking and over eating during the test period 4) Individuals who understand the purpose and contents of the experiment
Exclusion criteria
Exclusion criteria: 1)Subjects who are contracting or treating severe diabetes and kidney and/or liver diseases 2)Individuals who have a chronic diseases and regularly use drugs 3)Pregnant women, or women with intending to become pregnant, and lactating woman 4)Individuals participating or intending to participate in a drug administration test 5)Individuals judged by the doctor to be unsuitable
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin surface temperature of fingers and feet | — |
Secondary
| Measure | Time frame |
|---|---|
| Vas questionaire (1)cold intolerance of whole body (2)cold intolerance of limbs (3)fatigue (4)shoulder stiffness (5)quality of sleep (6)constipation | — |
Countries
Japan
Contacts
Univercity of Nagasaki Regional Partner Center