Sodium-containing versus sodium-trace preparations of IVIG for children with Kawasaki disease in the acute phase

Sodium-containing versus sodium-trace preparations of IVIG for children with Kawasaki disease in the acute phase - Sodium-containing versus sodium-trace preparations of IVIG for children with Kawasaki disease in the acute phase

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042763

Enrollment

42345

Registered

2020-12-16

Start date

2020-12-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kawasaki Disease

Interventions

High Na IVIG Low Na IVIG

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We used the Diagnostic Procedure Combination database to identify KD patients treated with IVIG between 2010 and 2017 and further identified those receiving high-Na and low-Na IVIG preparations as their initial treatment. The study outcomes included proportion of CAAs, proportion of IVIG resistance, length of stay, and medical cost. Propensity score-matched analyses were conducted to compare the outcomes between the two groups. Instrumental variable analyses were performed to confirm the results.

Exclusion criteria

Exclusion criteria: exclude patients with a suspected diagnosis of KD, inadequate treatment, and age over 6 years.

Design outcomes

Primary

Measure	Time frame
Coronary artery abnormalities	—

Countries

Japan

Contacts

Public ContactNobuaki Michihata

The University of Tokyo Department of Health Services Research, Graduate School of Medicine

gha10771@gmail.com0358411887

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026