Evaluation of the anti-glycation effect and damage reduction on the skin of ultraviolet rays by the test food.

Evaluation of the anti-glycation effect and damage reduction on the skin of ultraviolet rays by the test food: A randomized, double-blind, placebo-controlled, parallel-group, trial. - Evaluation of the anti-glycation effect and damage reduction on the skin of ultraviolet rays by the test food.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042757

Enrollment

Registered

2020-12-16

Start date

2020-12-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Japanese subjects

Interventions

Duration: 8 weeks Test food: Test food Administration: Take 1 tablet, three times a day. The daily dose of 3 tablets should be taken within the same day. If you miss a dose, take it when you noti

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) Subjects who are judged by a doctor to be eligible. 2) Subjects who can confirm 1MED in any of the 6 irradiation fields by MED (Minimal Erythema Dose) judgment. However, if the number of people who meet the conditions exceeds the number to be selected, those who can confirm 1 MED with a smaller irradiation energy will be selected.

Exclusion criteria

Exclusion criteria: 1) Subjects who treatment of illness. 2) Subjects who take medication.(antihistamines, anti-inflammatory agents, analgesics) on a regular basis. 3) Subjects who may show symptoms of skin allergies and skin hypersensitivity. 4) Subjects who are currently visit dermatologist. 5) Subjects who may have blisters due to sunburn. 6) Subjects with extremely thin upper arms. 7) Subjects with predisposition or scars on the medial upper arm of both arms that may affect the results of the test (diseases such as atopic dermatitis and urticarial, inflammation, eczema, trauma, acne, pimples, warts, stain, etc). 8) Subjects who cannot avoid sunburn due to long hours of outdoor work or sports from screening to the end of the test. 9) Subjects who plan to travel abroad or swim in the sea from screening to the end of the test. 10) Smoker. 11) Subjects who have been exposed to artificial ultraviolet rays within the past two months.

Design outcomes

Primary

Measure	Time frame
MED (Minimal Erythema Dose) judgment	—

Secondary

Measure	Time frame
1. Skin tone 2. Melanin amount and redness 3. Transepidermal water loss 4. Skin moisture content 5. Plasma Pentosidine	—

Countries

Japan

Contacts

Public ContactYushi Hashizume

Toyo Sugar Refining Co., Ltd. Research & Development Department

hashizume-y@toyosugar.co.jp0436-21-8127

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026