Healthy adults
Conditions
Interventions
Daily ingestion 7.2 g of Partially Hydrolyzed Guar Gum (PHGG) for 12 weeks.
Daily ingestion 7.2 g of dextrin for 12 weeks.
Sponsors
Hokkaido Information University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects who fully understand significance, content and purpose of this study and who agree to participate in this study with a written informed consent. 2. Subjects with relatively high score for 18 items related to psychological stress on The Brief Job Stress Questionnaire.
Exclusion criteria
Exclusion criteria: 1. Subjects who are under treatment or medication for autoimmune diseases, chronic inflammatory diseases or allergies. 2. Subjects who plan to receive influenza vaccination from the screening test date to the end of intake. 3. Subjects with serious cerebrovascular, cardiac, hepatic, renal, gastrointestinal or affected with infectious diseases which is required to report to the authorities. 4. Subjects who have a major surgical history such as gastrectomy, gastrorrhaphy, enterectomy or other serious gastrointestinal surgeries. 5. Subjects with unusually high and/or low blood pressure, abnormal physical data and/or abnormal hematological data. 6. Subjects with severe anemia. 7. Pre- or post-menopausal women complaining of obvious physical changes. 8. Subjects who are at risk of having allergic reactions to drugs, foods (especially soybeans or peanuts) and/or birch pollen. 9. Subjects who regularly take medicines (Antibiotics, immunosuppressants, anti-inflammatory drugs, antirheumatic drugs, antihistamines, antiallergic drugs, lactic acid bacteria preparations), functional food and/or supplements (mushrooms, seaweed, nucleic acids, yeast, lactobacillus, etc.) which would affect the immune function. 10. Heavy smokers, alcohol addicts or subjects with irregular lifestyle. 11. Subjects who donated either 400 ml whole blood within 16 weeks (women), 12 weeks (men), 200 ml whole blood within 4 weeks, or blood components within 2 weeks, prior to the current study. 12. Pregnant or lactating women or women who expect to be pregnant during this study. 13. Subjects who currently participate in other clinical trials, or participated within the last 4 weeks prior to the current study. 14. Subjects determined to be ineligible by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diary about cold-like symptoms at 6 and 12 weeks after beginning the intake of test food. | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary secretory IgA, number of NK cells, CD4/CD8 ratio, number of Treg cells, serum IgG, five fraction of leukocyte, serum cytokines (IFN-gamma, IL-10), organic acids in feces. | — |
Countries
Japan
Contacts
Public ContactNaoyuki HONMA
Hokkaido Information University Health Information Science Center
Outcome results
None listed