Study of primary sclerosing cholangitis using bile-derived organoids

Searching for Personalized Disease Mechanisms for Primary Sclerosing Cholangitis Using Human Bile-Derived Bile Organoids - Study on the disease mechanism of organoid-induced primary sclerosing cholangitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042727

Enrollment

Registered

2021-04-01

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Sclerosing Cholangitis

Interventions

Collect bile during ERCP for PSC patients Collect bile during ERCP for non-PSC patients

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing ERCP for liver, bile duct, or pancreas disease at our hospital who understand the contents of this study and have given written consent to participate in the study.

Exclusion criteria

Exclusion criteria: Patients who have requested to be excluded from the study The principal investigator or sub-investigator determines that the patient is ineligible to participate in the research

Design outcomes

Primary

Measure	Time frame
Identification of a new disease-specific mechanism using bile-derived bile duct organoids generated from PSC patients.	—

Secondary

Measure	Time frame
Changes in the morphology and inflammatory profile of bile-derived bile duct organoids among PSC patients or various diseases	—

Countries

Japan

Contacts

Public ContactNorihiro Imai

Nagoya University Hospital Department of Endoscopy

norihiro@med.nagoya-u.ac.jp0527412111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026