Healthy subjects
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy participants aged 20 to 84 years 2.Individuals who have no history of psychiatric disease 3.Individuals who are right-handed 4.Individuals who are consent to participate in this study 5.Critetria for elderly subject: 1) Individuals with Mini-mental state examination scores over 26 at screening, 2) Individuals with Clinical dementia rating scale score 0, 3)Individuals whose ADL is normal without any memory problems
Exclusion criteria
Exclusion criteria: 1.Individuals who have a history of traumatic brain injury with an unconsciousness lasting more than 5 minutes 2.Individuals who have a history of organic brain disease 3.Individuals who have a history of substance dependence 4.Individuals who are taking central nervous system stimulants 5.Individuals who have a history of disorders of consciousness and/or seizure 6.Individuals who have a chronic headache 7.Individuals who have a risk for MRI scan 8. Individuals who are considered unsuitable by doctors in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Elucidation of the binding capacity of the tracer by examining the level of changes before and after stimulation | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of the tracer binding with psychological and MRI data | — |
Countries
Japan
Contacts
Hamamatsu University School of Medicine Department of Biofunctional Imaging