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Study on brain serotonin release

Study on brain serotonin release - Serotonin release PET

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000042643
Enrollment
26
Registered
2021-01-15
Start date
2021-01-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Sponsors

Hamamatsu University School of Medicine
Lead Sponsor
Hamamatsu Medical Photonics Foundation Hamamatsu Photonics KK
Collaborator

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1.Healthy participants aged 20 to 84 years 2.Individuals who have no history of psychiatric disease 3.Individuals who are right-handed 4.Individuals who are consent to participate in this study 5.Critetria for elderly subject: 1) Individuals with Mini-mental state examination scores over 26 at screening, 2) Individuals with Clinical dementia rating scale score 0, 3)Individuals whose ADL is normal without any memory problems

Exclusion criteria

Exclusion criteria: 1.Individuals who have a history of traumatic brain injury with an unconsciousness lasting more than 5 minutes 2.Individuals who have a history of organic brain disease 3.Individuals who have a history of substance dependence 4.Individuals who are taking central nervous system stimulants 5.Individuals who have a history of disorders of consciousness and/or seizure 6.Individuals who have a chronic headache 7.Individuals who have a risk for MRI scan 8. Individuals who are considered unsuitable by doctors in charge

Design outcomes

Primary

MeasureTime frame
Elucidation of the binding capacity of the tracer by examining the level of changes before and after stimulation

Secondary

MeasureTime frame
Correlation of the tracer binding with psychological and MRI data

Countries

Japan

Contacts

Public ContactYasuomi Ouchi

Hamamatsu University School of Medicine Department of Biofunctional Imaging

ouchi@hama-med.ac.jp053-435-2466

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026