Dementias
Conditions
Interventions
Sponsors
Department of Biofunctional Imaging, Hamamatsu University School of Medicine
Hamamatsu Medical Photonics Foundation Hamamatsu Photonics KK
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Healthy participants aged 20 to 90 years 2.Individuals who have no history of psychiatric disease 3.Individuals who are right-handed 4.Individuals who are consent to participate in this study 5.Critetria for elderly subject: 1) Individuals with Mini-mental state examination scores over 26 at screening, 2) Individuals with Clinical dementia rating scale score 0, 3)Individuals whose ADL is normal without any memory problems 6. Patients with dementias (aged 20 to 90 years)
Exclusion criteria
Exclusion criteria: 1.Individuals who have a history of traumatic brain injury with an unconsciousness lasting more than 5 minutes 2.Individuals who have a history of organic brain disease 3.Individuals who have a history of substance dependence 4.Individuals who are taking central nervous system stimulants 5.Individuals who have a history of disorders of consciousness and/or seizure 6.Individuals who have a chronic headache 7.Individuals who have a risk for MRI scan 8. Individuals who are considered unsuitable by doctors in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Elucidation of pathophysiology of the diseases by examining the characters of CSF, blood and PET images for amyloid and tau. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of the tracer binding with psychological and MRI data | — |
Countries
Japan
Contacts
Public ContactYasuomi Ouchi
Hamamatsu University School of Medicine Department of Biofunctional Imaging
Outcome results
None listed