Healthy Subject
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Participants will be included on the following all criteria. 1)Not having difficulty in filling out Japanese explanatory documents, consent forms, and survey forms 2)Being able to stay in the examination room on the 5th floor of the Innovative Medical Research Institute, University of Tsukuba. 3)Having no sleep disorder currently being treated
Exclusion criteria
Exclusion criteria: Participants will be excluded from the experiment based on the following criteria. 1)Irregular lifestyle (Regular: sleep time between 9pm and 1am, wake time between 6am and 9am, 7-9 hours of sleep) 2)BMI less than 18.5 or greater than 25 3)Worked night shifts (after 10pm) 3 months prior to the experiment 4)Travel across time zones with time difference of 3 hours or more, 3 months prior to the experiment 5)Consumes alcohol regularly (40g (2 cans of beer) or more twice a week a more) 6)Smoker 7)Consumes more than 300mg (5 cups of 150mL) of coffee every day 8)MEQ score of less than 30 (extreme evening type) or greater than 70 (extreme morning type) 9)Pittsburgh Sleep Quality Index score of greater than 5.5 10)Those who have previously conducted the decision-making task which is used in this experiment 11)Claustrophobic 12)Pregnancy or its possibility 13)Lactation 14)Those who have a disease that may change suddenly or its history 15)Those who have been treated for psychiatric disorders or sleep disorders, and those who have symptoms that are currently being treated 16)Subjects judged by the investigator to be inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Amplitude of pre-REM negativity (PRN) at Fpz electrode | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Brain areas estimated as the current sources of PRN 2)REM density 3)Brain potentials using high density EEG 4)Sleep stage 5)Iowa gambling task (IGT) performance 6)Skin conductance response during IGT 7)Questionnaire about IGT 8)Psychomotor vigilance test performance 9)Subjective sleepiness and mood | — |
Countries
Japan
Contacts
University of Tsukuba International Institute for Integrative Sleep Medicine (WPI-IIIS)