The study of the relationship between experimental masticatory movement stimulation and brain-derived neurotrophic factor in healthy subjects

The study of the relationship between experimental masticatory movement stimulation and brain-derived neurotrophic factor in healthy subjects - The study of the relationship between experimental masticatory movement stimulation and brain-derived neurotrophic factor in healthy subjects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042553

Enrollment

Registered

2021-01-26

Start date

2021-01-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Gum chewing movement to placebo chewing movement Placebo chewing movement to gum chewing movement

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient who shows his/her will to participate in this study after obtaining informed consent through the substantial explanation on this investigation

Exclusion criteria

Exclusion criteria: Patients with systemic disease Patients taking medication Patient with smoking Patients with less than 24 functional teeth Patients with masticatory disorders Patients who are judged by investigators as being unsuitable because of other factors

Design outcomes

Primary

Measure	Time frame
Brain-derived neurotrophic factor levels in saliva and blood	—

Countries

Japan

Contacts

Public ContactTakuya Mino

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Oral Rehabilitation and Regenerative Medicine

gmd20107@s.okayama-u.ac.jp0862356682

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026