Primary osteoporosis
Conditions
Interventions
None listed
Sponsors
Koenji Orthopedics Clinic
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients who met the required inclusion criteria were enrolled in this study. 1. Patients with osteoporosis starting the treatment using ZOL from November 2016 to June 2019 at Koenji Orthopedics Clinic 2. Patients 55 years of age or older 3. Postmenopausal women who were diagnosed with primary osteoporosis
Exclusion criteria
Exclusion criteria: 1. Patients with a metabolic bone disease other than osteoporosis 2. Patients with a history of hypersensitivity to the study drug or BP 3. Patients who have severe renal impairment (creatinine clearance < 35 mL/min) at the start 4. Patients who are dehydrated (high fever, severe diarrhea and vomiting, etc.) at the start 5. Patients who have hypocalcemia at the start 6. Patients whom the physicians judged to be unsuitable because of idiosyncratic complications and markedly different background
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of change in the lumbar spine BMD. | — |
Secondary
| Measure | Time frame |
|---|---|
| The rate of change in the femoral neck BMD, the changes in type I procollagen N-terminal propeptide (P1NP), tartrate-resistant acid phosphatase-5b (TRACP-5b), VAS score of back pain, Japanese Osteoporosis Quality of Life Questionnaire (JOQOL). | — |
Countries
Japan
Contacts
Public ContactFumitoshi Omura
Koenji Orthopedics Clinic N/A
Outcome results
None listed