Efficacy of multiple gene panel testing for hereditary breast cancer and relevance to environmental factors

Efficacy of multiple gene panel testing for hereditary breast cancer and relevance to environmental factors - Efficacy of multiple gene panel testing for hereditary breast cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042523

Enrollment

Registered

2021-02-01

Start date

2021-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hereditary breast cancer

Interventions

mammography MRI annual chemotherapy for six months DNA damaging agents Radiotherapy omission Prophylactic Surgery mastectomy oophorectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Breast cancer meeting the criteria of genetic testing for BRCA1/2, TP53, PTEN, CDH1, or STK11

Exclusion criteria

Exclusion criteria: The patient judged as inappropriate by responsible doctor

Design outcomes

Primary

Measure	Time frame
Detection rate of pathogenic variant 5 years overall survival rate	—

Secondary

Measure	Time frame
Relationship between mutation of moderate risk gene and environmental factors	—

Countries

Japan

Contacts

Public ContactHiroyuki Maeda

Faculty of medicine, University of Fukui First Department of Surgery

maedah@u-fukui.ac.jp0776613111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026