Community-acquired (CAP) including COVID-19, hospital-acquired (HAP), and ventilator-associated pneumonia (VAP)
Conditions
Interventions
None listed
Sponsors
Nagoya University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The presence of a new infiltrate on a chest X-ray, or a computed tomography scan, plus at least one of the following criteria: 1) cough or purulent sputum, 2) pleuritic chest pain, 3) dyspnea, 4) fever or hypothermia (temperature >= 37.5 degrees or < 35 degrees), 5) white blood cell count >= 10,000 /mm3 or < 4,000 /mm3, 6) increase of CRP or PCT values above the upper limit of facility reference value and 7) hypoxemia (SpO2 < 90% or PaO2 < 60 Torr) or decline in oxygenation.
Exclusion criteria
Exclusion criteria: 1) Patients who do not receive initial empirical antibiotic treatment 2) Patients with obstructive pneumonia 3) Pneumonia occurred in other hospitals and patients who were transferred from their hospitals with a trend toward improvement 4) Patients whose pneumonia recurred within 3 days after the last day of antibiotic treatment of a preceding pneumonia episode 5) Patients who receive the treatment in outpatient clinics 6) Patients who are less than 20 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) 30-day mortality, 90-day mortality and in-hospital mortality 2) Identified pathogens and drug resistance 3) Early and late treatment failure 4) Severe adverse events 5) Readmission within 90 days after discharge 6) Appropriateness of antibiotic treatment | — |
Countries
Japan
Contacts
Public ContactYuichiro Shindo
Nagoya University Hospital Respiratory Medicine
Outcome results
None listed