Effect of Semaglutide 0.25mg on glycemic controls in type2 diabetes patients compared with dulaglutide 0.75mg.

Effect of Semaglutide 0.25mg on glycemic controls in type2 diabetes patients compared with dulaglutide 0.75mg. - Effect of Semaglutide 0.25mg on glycemic controls in type2 diabetes patients compared with dulaglutide 0.75mg.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042482

Enrollment

Registered

2020-11-18

Start date

2020-11-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type2 diabetes

Interventions

Patients who have received dulaglutide 0.75mg stop it and start receiving semaglutide 0.25mg. Patinets continue to receive it for 12 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) type2 diabetes 2) Patints who have received duraglutide 0.75mg 3) HbA1c fluctuation within 0.4% in the last year 4) Patints with the written informed consent

Exclusion criteria

Exclusion criteria: 1) Pationts received insulin 2) Patients with severe liver dysfunction 3) Patients with severe renal dysfunction(eGFR<30ml/min/1.73) 4) Patients with fasting serum CPR <0.5 or postprandial serum CPR <1.0 5) Patients taking steroid 6) Patients with malignant tumor currently undergoing treatment 7) Pregnant or lactating woman 8) Other patients who are judged to be unsuitable as subjects by the judgment of a doctor

Design outcomes

Primary

Measure	Time frame
Patients are goint to stop receiving dulaglutide 0.75mg and start receiving semaglutide 0.25mg. We compare HbA1c levels before receiving semaglutide 0.25mg with those after receiving semaglutide 0.25mg in 12 weeks.	—

Countries

Japan

Contacts

Public ContactTaichi Minami

Saiseikai Yokohamashi Nanbu Hospital Department of Diabetes and Endocrinology

ksqdd034@yahoo.co.jp045-832-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026