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How Is Standardized Mean Difference Computed, Reported and Interpreted in Randomized Controlled Trials

A Meta-epidemiological Study about How Standardized Mean Difference Is Computed, Reported and Interpreted in Randomized Controlled Trials - A Meta-epidemiological Study about How SMD Is Computed, Reported and Interpreted in RCTs

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000042464
Enrollment
60
Registered
2020-11-16
Start date
2020-11-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Not limited. General medicine, internal medicine, surgery, psychiatry, psychology.

Interventions

None listed

Sponsors

Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: We will include RCTs published on high-impact journals, which report any SMDs for any continuous outcomes. We restrict the eligible studies to those published on high-impact journals, because we consider that the method used compute the SMD would be better addressed, and results would be more comprehensively provided. Multifactorial RCTs, and crossover RCTs that report results of the first period are eligible.

Exclusion criteria

Exclusion criteria: We will exclude RCTs which use the term "effect size" or "SMD" in a nonspecific way (i.e. sample size calculation), but not for the outcome. We will exclude cluster randomization, quasi-randomized trials, and crossover RCTs whose first period result is not available.

Design outcomes

Primary

MeasureTime frame
(1) Study characteristics of RCTs that report SMD; (2) The term and method used to compute the reported SMD; (3) Comparison between reported SMD and SMD which we calculate based on different approaches

Secondary

MeasureTime frame
(1) How RCTs interpret the results in terms of SMD: focusing on whether it is comparable with previous studies (based on same method), and whether it is compared to a standard. (2) Relationship between reporting condition, calculation method and sub-discipline, journal.

Countries

Japan

Contacts

Public ContactYan Luo

Kyoto University Graduate School of Medicine Department of Health Promotion and Human Behavior

lilacluo@gmail.com+81-75-753-9491

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026