Randomised Control Trial for antimicrobial periodontal treatment for risk of stroke among diabetics

Randomised Control Trial for antimicrobial periodontal treatment for risk of stroke among diabetics - Randomised Control Trial for antimicrobial periodontal treatment for risk of stroke

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042458

Enrollment

Registered

2020-11-15

Start date

2020-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetics, Stroke, Periodontal disease

Interventions

Periodontal treatment will be given at the baseline followed in the week of 2, 4 and 6. For the test group, PERIOFEEL Dental Ointment 2% will be given to the periodontal pocket depth in which 4 mm or

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects who have HbA1c 6.0% or more. Treatment for diabetics has not been changed in the previous two month. As oral health criterial, subjects should have 10 or more present teeth and 4 or more among them have periodontal pocket depth in which 4 mm or more.

Exclusion criteria

Exclusion criteria: Subjects who have stroke and are smokers.

Design outcomes

Primary

Measure	Time frame
Effects of antimicrobial periodontal treatment will be assessed by changes of the LOX-index, in the week of 12 and 24	—

Countries

Japan

Contacts

Public ContactHiroshi Ogawa

Graduate School of Medical and Dental Sciences, Niigata University Faculty of Dentistry, Division of Preventive Dentistry

ogahpre@dent.niigata-u.ac.jp0252272857

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026