The augmented risk biomarkers of obesity-related diseases decrease after weight loss with diet or surgical removal of adipose tissue in patients with increased fat storage. Since the breast consists of mainly fat tissue, breast reduction surgery can lessen these augmented levels.
Conditions
Interventions
Breast reduction surgery Control was 6 months later
Sponsors
Celal Bayar University, School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women who requested breast reduction surgery. Each patient had breast hypertrophy with a distance between suprasternal notch and nipple greater than 28cm
Exclusion criteria
Exclusion criteria: Exclusion criteria were cardiovascular diseases, metabolic diseases such as diabetes and Cushing disease, connective tissue diseases, liver diseases, and endocrine disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative and six months after surgery the levels of fasting blood glucose, insulin, hemoglobinA1c, triglyceride, total cholesterol, low-density lipoprotein, high-density lipoprotein, small dense low-density lipoprotein, macrophage chemotactic protein-1, adiponectin, lipoprotein-associated phospholipase A2, pentraxin-3, chemerin, interferon-gamma, interleukin-6, tumor necrosis factor-alfa, and highly sensitive C reactive protein were compared using Wilcoxon sign test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Spearman correlation was used to investigate any relationship between the magnitudes of changes of the laboratory values and body mass index scores, and the amount of removed breast tissue. | — |
Countries
Asia(except Japan)
Contacts
Public ContactYavuz Kececi
Celal Bayar University Plastic and Reconstructive Surgery
Outcome results
None listed