Alzheimer'
Conditions
Interventions
None listed
Sponsors
Keio University School of Medicine, Department of Neuropsychiatry
Keio University, Faculty of Science and Technology Asaka Hospital Shonan Keiiku Hospital Tsutsuji Mental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: For Alzheimer's disease 1) Patients diagnosed with Alzheimer's disease according to the DSM-5 diagnostic criteria 2) Patients who have been judged by their doctors to have the capacity to make consent decisions and who have a full understanding of the study or who have received consent from a surrogate. For MCI 1) Patients diagnosed with MCI according to DSM-5 diagnostic criteria 2) Patients who have been judged by their doctors to have the capacity to make consent decisions and who have a full understanding of the study or who have received consent from a surrogate For healthy individuals 1) Healthy individuals with no history of mental illness who have volunteered to participate in the study through web advertisements, bulletin boards, email announcements, etc., or through their organizations
Exclusion criteria
Exclusion criteria: 1) Patients with some kind of physical disease that would make it difficult to measure EEG with a simple bipolar electroencephalography system (e.g., frontal skin disease or skull defect) 2) Patients with neurological or physical diseases that can affect EEG (e.g., brain tumor, stroke, epilepsy, disturbance of consciousness) 3) Patients receiving treatments that are likely to have a significant effect on EEG results (e.g., antiepileptic medication) 4) A person suffering from a mental illness other than dementia 5) When the principal investigator or sub-investigator decides that it is inappropriate to conduct
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG In particular, each frequency after the Fourier or Hilbert transforms and the amplitude variation of each frequency in the EEG during the measurement times will be involved. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination (MMSE) Montreal Cognitive Assessment (MoCA-J) Logical memory Stroop test Digit span test Trail making test B Word Fluency Test Ray Auditory Verbal Learning Test Rey -Osterrieth Complex Figure Test | — |
Countries
Japan
Contacts
Public ContactToshiro Horigome
Keio University School of Medicine Department of Neuropsychiatry
Outcome results
None listed