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Comparison of Alzheimer disease patients and healthy controls in easy Z-score imaging system with differential image reconstruction methods using SPECT/CT: Verification using normal database of our institution

Comparison of Alzheimer disease patients and healthy controls in easy Z-score imaging system with differential image reconstruction methods using SPECT/CT: Verification using normal database of our institution - Comparison of AD and Healthy in eZIS with differential image reconstruction methods using SPECT/CT: Verification using NDB of our institution

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000042362
Enrollment
50
Registered
2020-11-10
Start date
2020-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer disease

Interventions

None listed

Sponsors

Yamagata University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: AD patients: Detailed interview with a psychiatrist and patients positive for 11C-PiBPET Healthy controls: Those who do not have organic diseases by MRI etc.

Exclusion criteria

Exclusion criteria: Patients who are unsuitable for physical activity or test data during the test

Design outcomes

Primary

MeasureTime frame
In order to verify the difference between the two types of image reconstruction, we will create a VOI for eZIS analysis from the data of AD patients and healthy controlts acquired at our institution. eZIS analysis is performed on the analysis data, and ROC analysis is used to evaluate which of the image reconstruction FBP and OSEM methods has the higher differential diagnosis ability.—

Countries

Japan

Contacts

Public ContactMakoto Ohba

Yamagata University Hospital Department of Radiology

m-ohba@med.id.yamagata-u.ac.jp0236331122

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026