Healthy Adults
Conditions
Interventions
Ingest 3 tablets of test food A * in the first test and 3 tablets of test food B * in the second test, together with salt-loaded foods. In the third test, ingest 3 tablets of salt excretion supplement
Sponsors
Healthcare Systems Co., Ltd.
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Persons who received a sufficient explanation of the purpose and contents of the exam, have the capacity to consent, applied with free will with sufficient understanding, and agreed to participate with a written document 2. Healthy Japanese who are 20 years old or more and under 65 years old. 3. From persons who meet 2, preferentially select 30 persons with higher blood sodium delta AUC values at the time of screening, excluding those with outliers.
Exclusion criteria
Exclusion criteria: 1. Persons who have chronic illness, receiving medication, have a serious disease history 2. Persons who are allergic to the test food 3. Persons who regularly use medicines, foods for specified health use, health foods, etc. that may affect the amount of salt intake 4. Persons who have a history of hospital visits for hypertension treatment 5. Persons who have participated in other tests within the first month before the start of the test, or those who intend to participate in another exam after consenting to this exam 6. Persons who have a drinking habit (more than 3 days a week, 1 go or more in terms of sake per drinking day) 7. Persons who were judged as inappropriate for subjects by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood sodium delta AUC * Before ingestion, 30, 60, 90, and 120 minutes after ingestion. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total protein, albumin, neutral fat, total cholesterol, HDL-cholesterol, LDL-cholesterol, AST (GOT), ALT (GPT), ALP, gamma-GTP, CPK, total bilirubin, uric acid, urea nitrogen, creatinine, sodium, Blood levels of potassium, chlorine, calcium, iron, phosphorus, magnesium, LDH, hematocrit, blood osmotic pressure, renin activity, aldosterone. * Before ingestion, 30, 60, 90, and 120 minutes after ingestion. Postprandial urinary sodium, potassium, creatinine Blood pressure before and after ingestion (systolic blood pressure, diastolic blood pressure, pulse) | — |
Countries
Japan
Contacts
Public ContactTakamasa Masuda
Healthcare Systems Co., Ltd. Research and Development Department
Outcome results
None listed