Patients 18 years of age or older admitted to the ICU or HCU with a newly inserted central venous catheter or hemodialysis catheter
Conditions
Interventions
Intervention: 1.5% Oranexidine gluconate solution (Otsuka Pharmaceutical Factory, Inc.)
Control: 1% chlorhexidine alcohol (Toho Yakuhin Co.,Ltd)
Sponsors
Jichi Medical University Saitama Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients 18 years of age or older admitted to the ICU or HCU with newly inserted central venous or hemodialysis catheters.
Exclusion criteria
Exclusion criteria: 1) Patients with allergies to disinfectants 2) When the consent of the subject or his or her next of kin cannot be obtained 3) Patients with systemic skin diseases 4) The presence of a wound skin ulcer 5) When the catheter is replaced under the guidewire 6) Patients with antimicrobial catheters 7) Patients with antimicrobial-containing dressings 8) Patients participating in intervention trials related to CRBSI prevention (e.g., dressings, skin disinfectants, antimicrobial catheters, antimicrobial medications, etc.) 9) When it is judged to be difficult to obtain consent due to an emergency, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of catheter-related infections | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Incidence of catheter-related infections (per 1000 catheters/day) 2) In-hospital mortality rate 3) ICU mortality rate 4) Incidence of resistant bacteria (MRSA, Pseudomonas aeruginosa, VRE) 5) Adverse events (redness, urticaria, anaphylaxis, contact dermatitis etc.) | — |
Countries
Japan
Contacts
Public ContactHideto Yasuda
Jichi Medical University Saitama Medical Center Department of Emergency and Critical Care Medicine
Outcome results
None listed