Oral malodor
Conditions
Interventions
Sponsors
Matsumoto Dental University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subjects aged 50-74 years 2) Subjects who have volatile sulfur compounds in mouth air above the olfactory threshold (hydrogen sulfide =>1.5 ng/10 ml and methyl mercaptan =>0.5 ng/10 ml air)
Exclusion criteria
Exclusion criteria: 1) Subjects who have a history of serious disorders in liver, kidney, heart, lung, gastro-intestine, blood, endocrine system, or metabolic system etc. 2) Subjects who have dental treatment such as caries and periodontal disease 3) Subjects who had treatment with antibiotics in the past 1 month, or ones who are expected to have treatment with antibiotics 4) Subjects who participated in other clinical studies in the past 1 month 5) Subjects with milk allergy 6) Subjects who are judged inappropriate to this trial by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concentration of volatile sulfur compounds in oral air | — |
Secondary
| Measure | Time frame |
|---|---|
| Concentrations of hydrogen sulfide and methyl mercaptan in oral air, Evaluation of tongue-coating status, Oral moisture, Salivary multi-test system | — |
Countries
Japan
Contacts
Public ContactAkihiro Yoshida
Matsumoto Dental University Department of Oral Microbiology
Outcome results
None listed