Healthy female
Conditions
Interventions
Apply the test material on the left face and placebo on the right face respectively twice a day for 21 weeks.
Apply the test material on the right face and placebo on the left face respectively twice
Sponsors
Interface, Inc.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Japanese female aged from 40 to 59 years; (2) Subject who is willing to participate in the study and can comply with study requirements; (3) Subject who has any age spots on the left or right side of face; (4) Subject who has "crow's feet" wrinkles of grade 3 to 6 at the corners of both eyes; and (5) Subject who dehydrates face skin in winter.
Exclusion criteria
Exclusion criteria: (1) Subject who is pregnant or nursing, or is planning to become pregnant or nursing during the study; (2)Subject who used any drug, quasi-drug, or supplements, within 1 month before the baseline visit, that will affect the site to be examined; (3) Subject who has a skin disorder such as atopic dermatitis; (4) Subject who will take any skin care medication that may affect the results of the study; (5) Subject who experienced any cosmetic medication that may affect the results of the study; (6) Subject who is currently taking hormone replacement therapy; (7) Subject who is participating in any other clinical trials; and (8) Subject who otherwise disqualified from participation in the study for any reason at the discretion of the study physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hydration level of stratum corneum(0Weeks,13Weeks, and 21Weeks) | — |
Secondary
| Measure | Time frame |
|---|---|
| The activities on 0Weeks,13Weeks, and 21Weeks visits are as follows: Photographs of facial image: VISIA-Evolution (Spots, Brown spots, UV spots, Skintexture, Wrinkles, and Pores) Visual Evaluations Wrinkle Grade Evaluations Photographs of skin image: ANTERA 3D(Spots) Skin color: Chromameter CM-600d Skin color index: Mexameter Trans-epidermal water loss: Vapometer SWL5001JT Skin Viscoelasticity:Cutometer MPA580 Replicas Photographic Evaluations (Spots and Wrinkles) | — |
Countries
Japan
Contacts
Public ContactMiyuki Kodama
Interface, Inc. Not applicable
Outcome results
None listed