Healthy adults
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 20 to under 65 at the time of informed consent. 2. Men and Women 3. Those who defecate 2 to 5 times a week 4. Those who can drink 500 ml of water x 2 bottles a day 5. Those who can input electronic diary with smartphone / PC 6. Those who can obtain written consent
Exclusion criteria
Exclusion criteria: 1. Those who drink electrolyzed water (water generated by the generator) or hydrogen water on a daily basis 2. Currently being treated with drugs (abortive use is acceptable , but antibiotics and gastric acid secretion inhibitors cannot be used) 3. Those who have received antibiotics within the last 2 months 4. Those who have a current or history of serious illness 5. Those who have undergone surgical intestinal resection in the past 6. Those who take medicines, health foods, supplements, foods for specified health use, foods with functional claims that affect the intestinal function on a daily basis 7. Those who take yogurt and lactic acid bacteria drinks daily 8. Those who have a current or history of food allergies or drug allergies 9. Those who have excessive drinking habits 10. Those who have a smoking habit 11. Those who are currently pregnant or breastfeeding, or who wish to become pregnant during the test period 12. Those who are judged to be unsuitable for participation in this study by the investigators or the sub-investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Defecation survey (number of defecations, fecal properties by Bristol score, defecation volume, abdominal symptoms), stool short-chain fatty acid analysis, intestinal flora | — |
Secondary
| Measure | Time frame |
|---|---|
| Immune system markers (CD4, CD8), saliva sIgA measurement, endotoxin, serotonin | — |
Countries
Japan
Contacts
IMEQRD Co., Ltd Planning and Sales Department