hypothyroidism
Conditions
Interventions
Patients administrate LT4 before breakfast. Each timing regimen lasts for at least 4 weeks
before breakfast, after breakfast, at bedtime. The second cycle of testing is restricted to 2 medications, each tests again for 4-week treatment periods. To narrow the choice of medication from 3 to 2
Sponsors
University of Miyazaki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 Age over 20 years 2 Patients who have been receiving levothyroxine sodium hydrate for more than 6 months 3 Patients who selected to participate in the study after receiving a full explanation and with sufficient understanding
Exclusion criteria
Exclusion criteria: 1 Patients whose levothyroxine sodium hydrate dosage was changed within 3 months 2 Patient who judged inappropriate due to the complications and treatment by attending doctor 3 Patients with abnormal levels of TSH, FT4 or FT3
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of thyroid hormone for each method of administration | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Blood pressure and pulse rate for each method of administration 2) Medication adherence for each method of administration 3) Methods of administration selected by the patients at the end of trial | — |
Countries
Japan
Contacts
Public ContactTaisuke Uchida
Faculty of Medicine, University of Miyazaki Department of Neurology, Respirology, Endocrinology and Metabolism
Outcome results
None listed