The effect of anesthetic drugs on intraocular pressure during robot-assisted laparoscopic radical prostatectomy: comparison of remimazolam and desflurane

The effect of anesthetic drugs on intraocular pressure during robot-assisted laparoscopic radical prostatectomy: comparison of remimazolam and desflurane - The effect of anesthetic drugs on intraocular pressure during robot-assisted laparoscopic radical prostatectomy: comparison of remimazolam and desflurane

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042156

Enrollment

Registered

2020-10-20

Start date

2020-10-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer

Interventions

General anesthesia with remimazolam General anesthesia with desflurane

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) Elective robot-assisted laparoscopic radical prostatectomy is scheduled. 2) American Society of Anesthesiologists physical status is either 1, 2, or 3.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of glaucoma 2) Patients with a history of myasthenia gravis 3) Patients with past or family history of malignant hyperthermia 4) Patients with corneal disease 5) Patients taking any medications which can alter intraocular pressure 6) Patients with allergy to study drugs

Design outcomes

Primary

Measure	Time frame
The changes in intraocular pressure during surgery	—

Secondary

Measure	Time frame
Mean arterial pressure Peak inspiratory pressure End-tidal CO2 Ocular perfusion pressure Postoperative ocular complication	—

Countries

Japan

Contacts

Public ContactHiroe Shigeta

National hospital organization Tokyo medical center Anesthesiology

hiroe_y_0614@hotmail.co.jp03-3411-0111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026