Psychiatric disorders patients with chronic constipation
Conditions
Interventions
None listed
Sponsors
Nagisa clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with 20 years or older 2. Patients diagnosed with chronic constipation who had less than 3 defecation per week prior to administration of elobixibat 3. Outpatients diagnosed with depression, schizophrenia, bipolar disorder and anxiety disorder 4. Patients who were administrated elobixibat for at least 4 weeks continuously from July 1, 2018 to June 30, 2020 (Concomitant use of other drugs for the treatment of constipation should be allowed)
Exclusion criteria
Exclusion criteria: 1. Patients with a history of hypersensitivity to elobixibat 2. Patients with confirmed or suspected bowel obstruction due to a tumor or hernia 3. Patients with suspected constipation due to organic disease 4. Patients diagnosed with dementia 5. Patients who have been determined by a physician to be inappropriate to administrate elobixibat
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the stool frequency before and after 4 weeks of treatment by elobixibat | — |
Secondary
| Measure | Time frame |
|---|---|
| - Comparison of the stool frequency before and after 8, 12, 24, and 52 weeks of treatment by elobixibat - Use of concomitant drugs for constipation - Sub-analysis by the patients' background and the treatment status of elobixibat - Incidence rate and item of adverse events and adverse drug reaction - Discontinuation rate of elobixibat | — |
Countries
Japan
Contacts
Public ContactMasashi Sasa
Nagisa clinic Director of the clinic
Outcome results
None listed