Clinical research on hemodynamic predictors for the progression of major intracranial cerebrovascular stenosis using CFD analysis

Clinical research on hemodynamic predictors for the progression of major intracranial cerebrovascular stenosis using CFD analysis - CV Stenosis CFD Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000042113

Enrollment

650

Registered

2020-10-14

Start date

2020-10-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major intracranial artery stenosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Cases who have undergone cerebrovascular 3D contrast-enhanced CT examination or 3D cerebral angiography examination for which the original image DICOM data remain 2) Cases with about 30% or more stenosis found in the intracranial main artery (intracranial internal carotid artery, middle cerebral artery M1 portion, anterior cerebral artery A1 portion, intracranial vertebral artery, and basilar artery) by cerebrovascular imaging 3) Cases aged 20 years or older at the time of consent acquisition 4) Cases who have obtained the voluntary written consent of the patient (or his / her substitute)

Exclusion criteria

Exclusion criteria: 1) Cases with stenosis after irradiation 2) Cases with moyamoya disease 3) Cases with stenosis due to dissection 4) Cases with congenital stenosis 5) Cases after bypass surgery on the diseased side (registration is possible if there is an unoperated stenotic lesion on the contralateral side) 6) Patients after angioplasty of the lesion (registration is possible if there are other unoperated stenotic lesions) 7) When the principal investigator and the research coordinator judge that participation in this research is not appropriate

Design outcomes

Primary

Measure	Time frame
To identify hemodynamic factors that are significantly involved in the progression of major intracranial artery stenosis using computational fluid dynamics (CFD) analysis.	—

Secondary

Measure	Time frame
To identify hemodynamic factors that are significantly involved in the development of symptomatic cerebral infarction due to major intracranial artery stenosis using CFD analysis.	—

Countries

Japan

Contacts

Public ContactShunichi Fukuda

National Hospital Organization Kyoto Medical Center Department of Neurosurgery

fukudashunichi@gmail.com075-641-9161

Outcome results