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Diagnostic accuracy and adverse events of bronchial and intranasal challenge tests for NSAIDs-exacerbated respiratory disease: A systematic review and meta-analysis

Diagnostic accuracy and adverse events of bronchial and intranasal challenge tests for NSAIDs-exacerbated respiratory disease: A systematic review and meta-analysis - Diagnostic accuracy and adverse events of bronchial and intranasal challenge tests for NSAIDs-exacerbated respiratory disease: A systematic review and meta-analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000042096
Enrollment
Unknown
Registered
2020-10-15
Start date
2020-10-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NSAIDs-exacerbated respiratory disease

Interventions

None listed

Sponsors

Ichinomiyanishi Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: First, we will include the prospective or retrospective cohort studies, case-control studies, case series, and case reports describing aspirin inhalation challenge tests (bronchial or nasal challenge tests) for NERD in the review of adverse events. Second, AS and HS will independently select the articles from include articles in adverse events review for systematic review and meta-analysis of diagnostic accuracy. Inclusion criteria for diagnostic test accuracy review will be prospective or retrospective cohort studies, and case-control studies assessing the accuracy of aspirin or ketorolac inhalational challenge tests for differentiating NERD and non-NERD patients. Exclusion criteria of diagnostic test accuracy review will be case series, case reports, review articles, and animal studies.

Exclusion criteria

Exclusion criteria: Mentioned above.

Design outcomes

Primary

MeasureTime frame
Sensitivity and specificity—

Countries

Japan

Contacts

Public ContactAkihiro Shiroshita

Ichinomiyanishi Hospital Department of respiratory medicine

akihirokun8@gmail.com080-3807-4960

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026