Role of metabolic syndrome in carcinogenesis of esophageal-gastric junction

Association between metabolic syndrome and esophageal-gastric junction cancer - Association between metabolic syndrome and esophageal-gastric junction cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000042043

Enrollment

Registered

2021-03-17

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophago-gastric junction cancer

Interventions

samples of endoscopic biopsy from patients with esophago-gastric cancer samples of endoscopic biopsy from patients with gastric cancer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: esophago-gastric cancer and gastric cancer without current Helicobacter pylori infection

Exclusion criteria

Exclusion criteria: antibiotics/ steroid/ immunosuppressive medicine within one month history of chemo/ chemo-radiation treatment history of surgery for upper abdomen contraindication of endoscopic biopsy pregnancy/ mental disorder severe systemic disease others

Design outcomes

Primary

Measure	Time frame
Difference between mucosal barrier dysfunction of esophago-gastric junction by the stimulation of acidic bile acid salts and periodontobacillus between esophago-gastric junction carcinoma and gastric cancer	—

Countries

Japan

Contacts

Public ContactKaname Uno

Tohoku University Hospital Gastroenterology

kaname.uno.c3@tohoku.ac.jp819075640355

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026