Healthy adult
Conditions
Interventions
Food containing lactic acid bacteria for 8 weeks
Placebo (not containing lactic acid bacteria) for 8 weeks
Sponsors
Lotte Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Males and females from 20 to 59 years of age (2) Subjects giving written informed consent
Exclusion criteria
Exclusion criteria: (1) Individuals taking antiflatulents and/or laxatives (including purgative drug) and/or drugs which may affect immune function in common use (2) Individuals taking antibiotics and/or drugs which may affect digestion and absorption in common use (3) Individuals taking excessive amounts of foods containing lactic acid bacteria, bifidobacteria, natto bacteria, and/or other health foods including food for specified health use and food with function claim, which influence immune function (4) Individuals presenting known food allergy (5) Individuals who are pregnant or breast-feeding, or have the will of pregnancy during the study period (6) Individuals who have previous and/or current medical history of diseases (e.g., diabetes, liver disease, kidney disease, kidney disease) and/or immune-mediated diseases (e.g., atopic dermatitis, asthma, autoimmune disease) (7) Individuals who are under treatment or have a history of drug/alcohol dependence (8) Individuals who participate in other clinical studies or who are in willing to participate to these studies using foods, drugs and/or cosmetics (9) Individuals who are judged as unsuitable for the study by the investigator for the other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IgA flow rate of saliva | — |
Secondary
| Measure | Time frame |
|---|---|
| Conditioning questionnaire, concentration of IgA in saliva, saliva flow rate | — |
Countries
Japan
Contacts
Public ContactTomonori Ando
Lotte Co., Ltd. Central Laboratory , Food material development section
Outcome results
None listed