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Plaque progression from normal vessel wall to fibroatheroma: lessons from over 5-year follow-up optical coherence tomography study

Plaque progression from normal vessel wall to fibroatheroma: lessons from over 5-year follow-up optical coherence tomography study - Plaque progression from normal vessel wall to fibroatheroma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000042006
Enrollment
49
Registered
2020-11-01
Start date
2020-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

None listed

Sponsors

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients who underwent OCT imaging for native coronary artery were screened, we enrolled the patients who met the following inclusion and exclusion criteria into the present study. The inclusion criteria included patients 1) who underwent serial OCT imaging for native coronary artery over 5 years; 2) who underwent OCT for early atherosclerotic lesions located >5mm away from the stent edges, defined as diameter stenosis <30% on coronary angiography

Exclusion criteria

Exclusion criteria: The exclusion criteria included patients 1) who had undergone bypass graft surgery; 2) with chronic total occlusion lesions within the target vessel; 3) with poor OCT images; 4) who had undergone coronary revascularization within the same vessel during the follow-up period.

Design outcomes

Primary

MeasureTime frame
Presence of atheroma progression between Baseline and Follow-up

Secondary

MeasureTime frame
Baseline OCT findings and atheroma progression Serial changes of the intimal thickness during the follow-up period

Countries

Japan

Contacts

Public ContactRyo Takeshige

Department of Internal Medicine, Kobe University Graduate School of Medicine Division of cardiology

takeshige.kobe@gmail.com078-382-5846

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026