Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis with bilateral technique for cancer pain: a randomized trial

Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis with bilateral technique for cancer pain: a randomized trial - Study on comparison of pain relief effect between EUS-CGN and EUS-CPN with bilateral technique

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041999

Enrollment

Registered

2021-03-01

Start date

2021-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant tumor

Interventions

EUS-CGN EUS-CPN with bilateral technique

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) A malignant tumor has been diagnosed based on histopathological findings or imaging findings. 2) upper abdominal pain or back pain which the Visual Analogue Scale (VAS) is more than 4. 3) ECOG Performance status (PS) 3 or less. 4) Over 20 years old.

Exclusion criteria

Exclusion criteria: 1) Informed consent cannot be obtained 2) Communication is not possible due to consciousness disorder or mental disorder 3) Abnormal coagulation (PT-INR 1.5 or more) 4) Platelet count less than 50,000 / microL 5) Anticoagulants and antiplatelet agents cannot be discontinued 6) Presence of esophageal and/or gastric varices 7) Presence of abdominal plexus block before 8) Presence of alcohol intolerance 9) The examination responsibility or the attending doctor judged it to be inappropriate for the subject

Design outcomes

Primary

Measure	Time frame
Pain relief effect	—

Countries

Japan

Contacts

Public ContactNobuhiko Hayashi

University of Toyama Third Department of Internal Medicine

h.nobu.116@gmail.com076-434-7301

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026