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Clinical trial on the effects of dietary intake of sulforaphane-rich broccoli sprouts on severity of ulcerative colitis.

Clinical trial on the effects of dietary intake of sulforaphane-rich broccoli sprouts on severity of ulcerative colitis. - BS-UC-2020

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000041972
Enrollment
50
Registered
2020-10-01
Start date
2020-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ulcerative colitis

Interventions

Broccoli Sprouts (20 g/day, 8 weeks) Alfalfa Sprouts (20 g/day, 8 weeks)

Sponsors

University of Tsukuba
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age higher than 20 years. 2. Mild UC (Rachmilewits index less than 5) 3. Presence of maintenance therapy with mesalazine 4. Appropriate informed consent 5. Fecal Protectin level higher than upper limit of normal value

Exclusion criteria

Exclusion criteria: 1. Regular use of lactobacillus, steroids, immuno-modulators, biological drugs, caclineurin inhibitors, JAK kinase inhibitors. 2. Fecal Protectin level less than upper limit of normal value 3. Hospitalized Patients 4. Start of ASA treatment, or iIncrease in 5-ASA within 4 weeks 5. G-CAP or L-CAP treatment within 3 months 6. Treatment with herbal medicine including quingdao 7. Any other reasons judged by the principle investigator

Design outcomes

Primary

MeasureTime frame
Fecal calprotectin level (before and after 8 weeks treatment)

Countries

Japan

Contacts

Public ContactAkinori Yanaka

University of Tsukuba Hitachi Medical Education and Research Center

ynk-aki@md.tsukuba.ac.jp0294-23-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026