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Changes in cerebral blood flow and saliva volume induced by near-infrared radiation

Changes in cerebral blood flow and saliva volume induced by near-infrared radiation - Changes in cerebral blood flow and saliva volume induced by near-infrared radiation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000041952
Enrollment
20
Registered
2020-10-15
Start date
2020-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry mouse, bruxism, periodontal disease, and dementia

Interventions

Intraoral near-infrared radiation equipment is divided into eight blocks, and the gums are irradiated for a total of six minutes for 30 to 60 seconds per block. As the irradiation takes place, there i

Sponsors

Kanagawa dental university Division of Oral Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: People with no underlying disease

Exclusion criteria

Exclusion criteria: People who are sick or on long-term medication

Design outcomes

Primary

MeasureTime frame
Cerebral blood flow and saliva volume will be measured before the study begins. Saliva will be collected using a salivator and resting saliva volume will be measured. Next, the subjects will wear near-infrared spectroscopy (NIRS) and be irradiated with near-infrared radiation for 30 seconds to one minute at a time in eight blocks according to the irradiation manual. The subjects were irradiated with near-infrared light for 30 seconds to one minute at a time, according to the irradiation manual, in eight blocks. The rate of change in the signal at this time was measured by NIRS. As a control, we will measure the change in cerebral blood flow rate of the gingival massage in the same order and at the same time as the experimental group.

Secondary

MeasureTime frame
Near-infrared irradiation was continued for one week at home after brushing the teeth at night according to the irradiation manual, and saliva was collected again after one week to compare saliva levels.

Countries

Japan

Contacts

Public ContactWakako Sakaguchi

Kanagawa dental university Division of Oral Sciences

sakagichi@kdu.ac.jp046-822-9537

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026