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Prospective study for evaluating hepatic steatosis using Ultrasound-guided attenuation parameter (UGAP) and Controlled Attenuation Parameter (CAP) by comparison with MRI-determined proton density fat fraction (PDFF)

Prospective study for evaluating hepatic steatosis using Ultrasound-guided attenuation parameter (UGAP) and Controlled Attenuation Parameter (CAP) by comparison with MRI-determined proton density fat fraction (PDFF) - Ultrasound-guided attenuation parameter (UGAP) vs Controlled Attenuation Parameter (CAP) study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000041902
Enrollment
200
Registered
2020-09-27
Start date
2020-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic liver disease

Interventions

None listed

Sponsors

Yokohama City University School of Medicine Department of Gastroenterology and Hepatology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.NAFLD patients who underwent UGAP, CAP and PDFF within 3 months 2. As control subjects without steatosis, patients with chronic liver disease including viral hepatitis, NAFLD, autoimmune hepatitis, primary biliary cholangitis, and so on. 3.Patients who can follow instructions such as breath-holding.

Exclusion criteria

Exclusion criteria: 1.Patients without claustrophobia 2.Patients without magnetic substance or tattoo 3.Patients without pacemakers 4.Patients who are pregnant 5.Patients judged as inappropriate for the study by the study responsibility (share) physician.

Design outcomes

Primary

MeasureTime frame
We assess the accuracy of UGAP and CAP in assessing hepatic steatosis compared to PDFF

Secondary

MeasureTime frame
We verify whether UGAP and CAP can diagnose fatty liver (liver fat content 5% or more)

Countries

Japan

Contacts

Public ContactKento Imajo

Yokohama City University School of Medicine Department of Gastroenterology and Hepatology

kento318@yokohama-cu.ac.jp+81457872640

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026