The study of cardiovascular complications in osteogenesis imperfecta in adulthood

The study of cardiovascular complications in osteogenesis imperfecta in adulthood - The study of cardiovascular complications in osteogenesis imperfecta in adulthood

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041901

Enrollment

100

Registered

2020-09-27

Start date

2020-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteogenesis imperfecta

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients between the ages of 30 and 79 years old who were diagnosed with osteogenesis imperfecta in a medical institution.

Exclusion criteria

Exclusion criteria: Patients who have received treatment for either cerebrovascular or cardiac disease. Other patients who are deemed by the investigators to be unsuitable as subjects

Design outcomes

Primary

Measure	Time frame
(A) Heart rate and blood pressure (B) Echocardiography (presence of valvular disease, left ventricular myocardial thickness, left ventricular diameter, left ventricular ejection fraction, aortic valve diameter, Valsalva sinus diameter, ST junction diameter, descending aorta diameter) (C) Head MRI and MRA (presence of cerebral aneurysm (defined as more than 2 mm) and size). Head MRI includes the evaluation of presence of basilar impression	—

Measure

Time frame

(A) Heart rate and blood pressure (B) Echocardiography (presence of valvular disease, left ventricular myocardial thickness, left ventricular diameter, left ventricular ejection fraction, aortic valve diameter, Valsalva sinus diameter, ST junction diameter, descending aorta diameter) (C) Head MRI and MRA (presence of cerebral aneurysm (defined as more than 2 mm) and size). Head MRI includes the evaluation of presence of basilar impression

—

Countries

Japan

Contacts

Public ContactYoshihiko Kodama

University of Miyazaki Hospital Department of pediatrics

kodamayoshihiko@gmail.com0985-85-0989

Outcome results