Locally advanced non-small cell lung cancer, post-operative recurrence of non-small cell lung cancer
Conditions
Interventions
Patients recieved SIB-IMRT using VMAT, and total dose was 69Gy and 51Gy in 30 fractions for gross tumor and elective lymph node.
Sponsors
Hyogo College of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) pathologically proven clinical stage-II or III non-small cell lung cancer, or loco-regional recurrence after surgery or chemotherapy, 2) non-surgical candidate, 3) no distant metastasis 4) aged 20 or over, 5) performance status: 0 or 1, 6) A written informed consent was obtained
Exclusion criteria
Exclusion criteria: 1) history of thoracic irradiation 2) with uncontrollable co-morbidity 3) with other active double primary cancer 4) with interstitial pneumonitis or pulmonary fibrosis 5) in pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival rate at three years after radiation therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| the progression free survival at three years after radiation therapy, the incidence and degree of radiation pneumonitis, relationship between radiation pneumonitis and dosimetric factors the incidence of adverse effects the validity of re-treatment planning using the DIR software, the validity of adoptive radiation therapy with cone beam CT, determining the optimal re-planning period, the influence of the changes of body contour for the accuracy of IMRT | — |
Countries
Japan
Contacts
Public ContactMasayuki Fujiwara
Hyogo College of Medicine Department of Radiology
Outcome results
None listed