A prospective observational study on mechanism of pulmonary fibrosis and a signature molecule based on pathology of progressive fibrosing interstitial lung diseases

A prospective observational study on mechanism of pulmonary fibrosis and a signature molecule based on pathology of progressive fibrosing interstitial lung diseases - A prospective observational study on mechanism of pulmonary fibrosis and a signature molecule based on pathology of progressive fibrosing interstitial lung diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041871

Enrollment

Registered

2020-10-01

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial lung diseases

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with interstitial lung disease s (ILDs) In patients with acute phase,treated o r untreated are eligible. In patients with chronic disease,untrea ted are eligible. 2. Participants must be fully informed abo ut the study and signed a written infor med consent.

Exclusion criteria

Exclusion criteria: 1. Cases not possible to cooperate with ex aminations such as pulmonary function t ests. 2. Cases with active respiratory infectio n. 3. Cases in which informed consent was obt ained for this study. 4. Cases judged by the attending physicia n to be an ineligible.

Design outcomes

Primary

Measure	Time frame
The differences in subsets and activation of T cells, B cells, macrophages, and granulocytes in bronchoalveolar lavage fluid and peripheral blood is compared with or without pulmonary fibrosis. Investigate the relationship between such deviation on cellular subsets and/or activation with later prognosis of ILD patients at 12 months.	—

Countries

Japan

Contacts

Public ContactTsukie Tsukuda

Kochi Medical School, Kochi University Department of Respiratory Medicine and Allergology

jm-tkky@kochi-u.ac.jp088-880-2345

Outcome results