Superficial non-ampullary duodenal epithelial tumor
Conditions
Interventions
Partial injection underwater endoscopic mucosal resection (PI-UEMR) Sodium hyaluronate is used for submucosal injection agent.
Underwater endoscopic mucosal resection (UEMR)
Sponsors
Keio University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients over 20 years of age scheduled for endoscopic treatment of lesions diagnosed as non-ampullary duodenal adenoma of 13-20 mm 2) Tumors without stalk 3) Patients who agreed to participate in the study
Exclusion criteria
Exclusion criteria: 1) Cases in which snaring is considered difficult due to poor maneuverability 2) Cases in which suspected submucosal invasive cancer 3) Cases of chronic kidney disease needs dialysis 4) Cases of uncompensated liver cirrhosis 5) Cases of hematologic disease with coagulation dysfunction 6) Cases where antithrombotic management is not possible according to the guidelines of the Japan Gastroenterological Endoscopy Society (Case of a low dose aspirin is enable to treatment without drug withdrawal. 7) Cases of other critical organ failure 8) Cases of multiple duodenal tumors associated with hereditary bowel diseases (i. e; familial colorectal polyposis) 9) Other casess deemed ineligible at a preoperative conference
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| En bloc resection rate with pathologically confirmed negative margins without conversion to ESD (R0 resection rate) | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of submucosal injection agents, procedure time, en bloc resection rate, macroscopic and pathological margin, intra- and post operation complication, conversion rate to ESD | — |
Countries
Japan
Contacts
Public ContactYusaku Takatori
Keio University School of Medicine Cancer Center
Outcome results
None listed