Efficacy of serratus anterior plane block for postoperative analgesia in Minimally Invasive Cardiac Surgery

Efficacy of serratus anterior plane block for postoperative analgesia in Minimally Invasive Cardiac Surgery: a randomized, double-blind, controlled trial - Efficacy of serratus anterior plane block for postoperative analgesia in Minimally Invasive Cardiac Surgery: a randomized, double-blind, controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041814

Enrollment

Registered

2020-09-16

Start date

2020-09-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical pain after Minimally Invasive Cardiac Surgery

Interventions

Twenty mL of 0.9% saline administration through the catheter for the serratus anterior plane block at 6-hour interval to 5 days after surgery Twenty mL of 0.25% ropivacaine administration through the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Elective patient who undergo Minimally Invasive Cardiac Surgery with lateral thoracic approach 2.ECOG performance status 0-2

Exclusion criteria

Exclusion criteria: 1.History of thoracotomy 2.History of cardiac surgery 3.Long-term use of opioids 4.Use of analgesic more than 2 months 5.Allergy to local anesthetics 6.Liver failure, renal insufficiency 7.Infection at the block site 8.Pregnancy 9.Phsychiatric disease

Design outcomes

Primary

Measure	Time frame
Fentanyl consumption in the first 5 days after surgery	—

Secondary

Measure	Time frame
1.Numerical rating pain scale at rest and moving 2.Length of intensive care unit stay 3.Length of hospital stay 4.Serum concentrartion of ropivacaine 5.Serum concentrartion of fentanyl 6.Short Physical Performance Battery score, walking distance for 6 minutes, grip strength, perimeter of the thorax, range of motion angle at the upper limb joint 7.Incidence of nausea and vomitting 8.Incidence of ropivacaine-induced adverse events 9.Number of use of additional analgesics 10.Time to the first use of fentanyl in intavenouse patient-controlled analgesia 11.Time from discontinuation of fentanyl administration during mechanical ventilation to reinitiation of fentanyl administration for analgesia 12.Transthoracic echocardiography before and after surgery	—

Measure

Time frame

1.Numerical rating pain scale at rest and moving 2.Length of intensive care unit stay 3.Length of hospital stay 4.Serum concentrartion of ropivacaine 5.Serum concentrartion of fentanyl 6.Short Physical Performance Battery score, walking distance for 6 minutes, grip strength, perimeter of the thorax, range of motion angle at the upper limb joint 7.Incidence of nausea and vomitting 8.Incidence of ropivacaine-induced adverse events 9.Number of use of additional analgesics 10.Time to the first use of fentanyl in intavenouse patient-controlled analgesia 11.Time from discontinuation of fentanyl administration during mechanical ventilation to reinitiation of fentanyl administration for analgesia 12.Transthoracic echocardiography before and after surgery

—

Countries

Japan

Contacts

Public ContactYUNA SATO

Sendai Kousei Hospital Department of Anesthesiology

y0u1n0a4@gmail.com022-222-6181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026