Eye disease
Conditions
Interventions
Oral administration of food containing water chestnut peel extract/lutein(Sante Wellvision), 2 tablets once a day for 3 months
Sponsors
Shimane university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Outpatient 2)20 years old and over, 75 years old and under 3)Willingness to provide written informed consent 4)Those who have a stable eye disease and are judged by the investigator that there is no need to change the ophthalmic drug or surgery within three months after participating in this study 5)Those who want to take Sante Wellvision 6)BCVA: 0.5 or more for both eyes 7)Intraocular pressure: 20mmHg or less for both eyes (Goldmann applanation tonometer) 8)Vegimeter measurement index value: 352 (Japanese average 95 percent confidence interval upper limit) or less 9)AGEs sensor measurement value: 0.49 (non-diabetic Japanese average 95 percent confidence interval lower limit) or more
Exclusion criteria
Exclusion criteria: 1)severe systemic diseases 2)Those who are more likely to have decreased visual acuity and increased intraocular pressure within 3 months due to progression of eye disease 3)Smoker 4) Those who have a continuous intake habit of supplements that advocate anti-oxidation and anti-glycation over the past 6 months, or are scheduled to take supplements during this study period 5) Those who may change their lifestyle during this study period 6)Pregnant, lactating, or possibly pregnant 7)Those who may have allergic reactions to food containing water chestnut peel extract/lutein, and serious allergic reactions to other foods or drugs 8)Those who are judged to be ineligible for the purpose of this study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change value/change rate in fingertip skin-measured AGEs/carotenoid levels 3 months after ingestion of food containing water chestnut peel extract/lutein | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in blood pressure, body weight, corrected visual acuity, and intraocular pressure | — |
Countries
Japan
Contacts
Public ContactYukari Yamane
Shimane university faculty of medicine Department of Ophthalmology
Outcome results
None listed