Coronary artery disease
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with SAP or ACS who are undergoing catheterization would be eligible. ACS include ST elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI), and unstable angina pectoris. When thrombus interferes with optimal OCT image acquisition, aspiration thrombectomy will be allowed.
Exclusion criteria
Exclusion criteria: - Previous revascularization at the culprit vessel - Tortuous vessel - Heavily calcified vessel - Chronic Kidney Disease (estimated glomerular filtration rate < 30 mL/min per 1.73 m2) - Cardiogenic shock
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aims of the study are (1) to evaluate the prevalence and pattern of layered plaques both at culprit and non-culprit lesions using optical coherence tomography (OCT) in a prospective fashion, and (2) to identify biomarkers and microbiome specific for layered plaque to better understand the underlying pathobiology. | — |
Countries
Japan
Contacts
New Tokyo Hospital Clinical research center