Effects of stimulation frequency in peripheral nerve stimulation on the primary motor cortex excitability in healthy subjects: a crossover randomized controlled trial

Effects of stimulation frequency in peripheral nerve stimulation on the primary motor cortex excitability in healthy subjects: a crossover randomized controlled trial - Effects of stimulation frequency in peripheral nerve stimulation on the primary motor cortex excitability in healthy subjects: a crossover randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041690

Enrollment

Registered

2020-09-05

Start date

2020-02-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Peripheral electrical stimulation Frequency: 100 Hz Intensity: above sensory threshold Pulse width: 250 microsecond Stimulation time: 60 minutes Peripheral electrical stimulation Frequency: 1

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Age: from 20 to 60 years old 2) Obtaining agreement to this study

Exclusion criteria

Exclusion criteria: 1) A history of orthopedic disease 2) A history of neurological diseases 3) Contraindicated to transcranial magnetic stimulation 4) Contraindications to peripheral electrical stimulation 5) Persons are deemed unsuitable by researchers or physicians

Design outcomes

Primary

Measure	Time frame
Motor evoked potentials before stimulation, at 15, 30, 45, 60, 65, 70, and 75 minutes after stimulation	—

Countries

Japan

Contacts

Public ContactDaisuke Kubo

Tokai university hospital Department of rehabilitation services

d.bokukubo@tokai.ac.jp0463-93-1121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026