Healthy person
Conditions
Interventions
Collagen from fish
Non-denatured collagen from fish
placebo
Sponsors
Linise Co., Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Men and women whose age at the time of obtaining consent is 40 to 70 years old 2) People with discomfort in their knees 3) Kellgren-Lawrence (K-L) classification grade 0-2 4) Those who have sufficiently explained the purpose and contents of the research, have the ability to agree, have volunteered to participate in the test after understanding it well, and consented to the test in writing.
Exclusion criteria
Exclusion criteria: 1. with hyperuricemia and gout attack 2.Providing medical and physical therapy treatments for knees 3.Person who has a history of knee surgery or knee surgery is necessary 4.We regularly use health foods that affect the test results and continue to take them during the test period. 5. I regularly use drugs that affect the evaluation of this study. 6. Ingestion of drugs that affect bone metabolism markers 7.Intra-articular injection of hyaluronic acid or steroids 8. Need joint drug therapy during the test period 9. Surgery planned regardless of knee during the test period 10. Routine physical activity 11. History of bone and joint related diseases such as fractures and sprains within the past 3 months 12. Those who are judged to be unsuitable as subjects from the answers to the lifestyle habits 13. Disqualification as a result of clinical laboratory test 14. Taking warfarin due to cerebral infarction or heart disease 15. Test food may cause allergies 16. History of malignant tumor 17. Lactating, pregnant, and planning to become pregnant during the study 18. Participating in other clinical trials at the start of this study 19. In addition, the investigator determined that the patient was ineligible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluated by the subject (JKOM and VAS ) | — |
Secondary
| Measure | Time frame |
|---|---|
| Markers for collagen(C1,2C, CPII, CTX-II) | — |
Countries
Japan
Contacts
Public ContactYoshihiro Otake
feileB Co.Ltd Clinical Trial Support Department
Outcome results
None listed