Healthy volunteer
Conditions
Interventions
Intake of test food for 12 weeks (1 capsule per day)
Intake of placebo food for 12 weeks (1 capsule per day)
Sponsors
DRC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Healthy male and female whose age from 30 to 59 years old at the time informed consent. 2) Subjects whose Fitzpatrick skin phototype is type II or type III. 3)Subjects who accept the analysis for UV-induced erythema in their back skin. 4)Subjects whose basement MED is judged as second, third or fourth points in six-grade UV-irradiated area before intake of the test food. 5)Subjects who are aware of skin dryness and roughened. 6)Subjects who can visit to the administrative facility on every inspection day. 7)Subjects who have received a sufficient explanation of the purpose and contents of the examination, have the ability to make a self-judgment, voluntarity participate in the study after understanding the content enough and agree to participate in the study by signing the written informed consent.
Exclusion criteria
Exclusion criteria: 1)Subjects with photosensitivity disorder. 2)Subjects who take medicine that affect light sensitivity of skin. 3)Subjects who regularly go to a dermatology office. 4)Subjects who continuously take medicine, quasi-medicine, functional food or supplement which advocate or emphasize efficacy for which is evaluated in the trial. 5)Subjects who have skin disease or abnormality such as atopic dermatitis. 6)Subjects who may perform physical activity in the sunlight for a long time during test period. 7)Subjects who take anti-inflammatory medicine at least once a month. 8)Shift worker. 9)Subjects who receive or require medical or prophylactic treatment. 10)Subjects who have a medical history for severe disease or abnormality in glucose or lipid metabolism, endocrine or nerve system, or for psychiatric disorder. 11)Subjects who have a medical history or present illness of serious hepatopathy, kidney damage, heart disease, hematological and blood disease. 12)Subjects who have a medical history of serious gastrointestinal disease. 13)Subjects who have a medical history of alcoholism or drug addiction. 14)Subjects who have risk for allergy related to test foods. 15)Subjects who have s damage or inflammation on the measurement sites. 16)Subjects who have Severe anemia. 17)Subjects whose BMI is over 30.0 kg/m2 18)Subjects who smoke. 19)Subjects who will develop seasonal allergy symptoms like hay fever and take medicine. 20)Subjects who had been conducted an operation or beauty treatment on the measurement sites within the past 6 months. 21)Subjects who frequently intake food which might affect skin color. 22)Subjects who show abnormality in blood test during screening and test period. 23)Possible pregnancy, pregnancy and lactation 24)Subjects who were involved in another clinical studies within 4 weeks prior to the trial, or who will participate in another clinical studies. 25)Subjects who are judged to be inappropriate for the study by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MED(minimal erythema dose) | — |
Secondary
| Measure | Time frame |
|---|---|
| Transepidermal water loss Stratum corneum water content Skin color (L*, a*, b*) Photography of the irradiated area | — |
Countries
Japan
Contacts
Public ContactYuri Okano
CIEL CO., LTD. CIEL CO., LTD.
Outcome results
None listed