Pathological and biological assessment of arterial thrombus retrieved from infarct-related artery in patients with or without atrial fibrillation

Pathological and biological assessment of arterial thrombus retrieved from infarct-related artery in patients with or without atrial fibrillation - Macrophage in thrombus study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041615

Enrollment

100

Registered

2020-08-31

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke and acute myocardial infarction

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: stroke within 6 hours from symptom onset, acute myocardial infarction within 12 hours from symptom onset, successfully retrieved thrombus from infarct-related artery

Exclusion criteria

Exclusion criteria: hepatic disease, renal failure(eGFR<30), active malignancy, collagen disease, contraindication of emergent catheter treatment, not suitable for the inclusion judged by operator.

Design outcomes

Primary

Measure	Time frame
Distribution of M1, M2 macrophage in thrombus	—

Secondary

Measure	Time frame
classification of thrombus defined as follows; fresh, lytic, organized, markers in thrombus, biomarkers in serum	—

Countries

Japan

Contacts

Public ContactTomomi Koizumi

National Hospital Organization Mito Medical Center Division of Cardiovascular Medicine

tkoizumioffice@gmail.com+81292407711

Outcome results