Clinical characteristics of primary aldosteronism and differences between primary aldosteronism and essential hypertension

Clinical characteristics of primary aldosteronism and differences between primary aldosteronism and essential hypertension - Clinical characteristics of primary aldosteronism and differences between primary aldosteronism and essential hypertension

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041602

Enrollment

1000

Registered

2020-08-29

Start date

2020-08-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary aldosteronism

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who were diagnosed with primary aldosteronism and essential hypertension at Nihon University Itabashi Hospital. (January 2006-July 21, 2025) 2. Patients who were diagnosed with primary aldosteronism and essential hypertension at Tokyo Medical and Dental University Hospital, Affiliated Hospital of Chongqing Medical University, Monash University, and Hudson Institute of Medical Research. (January 2006-July 21, 2025)

Exclusion criteria

Exclusion criteria: Patients who refused to participate in this study and the investigator determined to be unsuitable for study

Design outcomes

Primary

Measure	Time frame
age, gender, blood pressure, BMI, blood tests (serum biochemistry test, daily fluctuation of hormones, etc.), urinalysis, confirmatory tests(captopril challenge test, furosemide and upright posture test, saline infusion test), contrast CT examination, adrenal vein sampling, portable polysomnography, ankle brachial pressure index, cardiac ultrasound, abdominal ultrasound, carotid ultrasound	—

Secondary

Measure	Time frame
Proteins presumed to be involved in primary aldosteronism, comprehensive protein profiling using omics platforms, and non-coding RNA	—

Countries

Japan,Asia(except Japan),Australia

Contacts

Public ContactHiroki Kobayashi

Nihon University School of Medicine Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine

kobayashi.hiroki@nihon-u.ac.jp+81-3-3972-8111

Outcome results