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The clinical evaluation of topical nanoencapsulation retinol combination cosemtic for wrinkles of the skin

The clinical evaluation of topical nanoencapsulation retinol combination cosemtic for wrinkles of the skin - The clinical evaluation of topical nanoencapsulation retinol combination cosemtic for wrinkles of the skin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000041544
Enrollment
12
Registered
2020-09-01
Start date
2020-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe wrinkles around eyes

Interventions

Application of the test cosmetic A to the one side of the face, Application of the test cosmetic B to the another side of the face, 8 weeks, twice a day Application of the test cosmetic C to the one

Sponsors

Nanoegg Research Laboratories, Inc.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) 6 to 7 wrincle grade in eye area 2) Individuals who can visit to clinic (Japanese males and females) 3) Individuals providing written informed consent 4) Individuals not younger than 20 years old at the time of informed consent

Exclusion criteria

Exclusion criteria: 1) Individuals who are sensitive to test product 2) Individuals who are or are possibly pregnant, or are lactating 3) Individuals with severe skin diseases 4) Individuals without capacity to consent 5) Individuals judged inappropriate for the study by a doctor

Design outcomes

Primary

MeasureTime frame
Questionnaire and observation for skin condition on before study starting and 4 weeks and 8 weeks after study starting

Secondary

MeasureTime frame
Investigating of VISIA, skin viscoelasticity, TEWL, erythema, water content in the corneal layer, and replica of wrinkles around eyes on before study starting and 4 weeks and 8 weeks after study starting

Countries

Japan

Contacts

Public ContactYoshiki Kubota

Nanoegg Research Laboratories, Inc. Pharmaceutical Products Research and Development Section

rdm@nanoegg.co.jp044-400-1155

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026